Single-Cell World

Single-Cell World

AGBT 2026: Key Trends Shaping the Future of Single-Cell Technology

Cátia Moutinho's avatar
Cátia Moutinho
Mar 05, 2026
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Every year I look forward to the Advances in Genome Biology and Technology (AGBT) General Meeting as something like a “state of the union” for genomics technologies.

Not because every major launch happens there, but because the meeting usually reveals what the next 6–12 months will look like for the field. It also gives me plenty of topics to write ✍️ about.

This year, the signals around single-cell technologies were subtle but meaningful. Instead of dramatic launches, the focus shifted to:

  • 🔬 scaling experiments

  • ⚙️ improving workflows

  • 🧠 enabling more complex biological questions

Below is a recap of the main updates I could gather from the meeting.

📅 Next Tuesday I’ll publish a second article focused on the spatial biology updates from AGBT 2026.

AGBT 2026 infographic showing three major trends in single-cell technology: larger-scale experiments, improved workflows, and more dynamic biological analysis.
Figure 1. Key signals for single-cell technologies emerging from AGBT 2026: scaling experiments, improving workflows, and enabling more dynamic biological studies.

Industrial-scale Single-cell Workflows 🏭

Roche’s new sequencer: AXELIOS 1

One of the most talked-about launches at the meeting was Roche’s new sequencer, AXELIOS 1, built around SBX (sequencing by expansion).

Why does this matter for single-cell?

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